If an injecting drug user exhausts accessible veins, then the user may inject drugs into the penis.
Drugs implicated:
(1) cocaine
(2) heroin
(3) buprenorphine
(4) other injected drug of abuse
Pathogenesis:
(1) vasoconstriction
(2) chemical impurities
(3) drug additives (levamisole, other)
(4) thrombosis
(5) infection
Complications:
(1) ulceration
(2) thrombosis
(3) fibrosis (including phimosis)
(4) necrosis, including Fournier's gangrene
(5) cellulitis or abscess