Kone-Paut et al developed a classification tool to identify a pediatric patient with Behcet’s disease. The authors are from the international PEDBD group.
Behcet’s disease is described as a variable vessel vasculitis.
Patient selection: onset of first symptom before 16 years of age
Parameters:
(1) recurrent oral aphthosis
(2) genital ulceration or aphthosis
(3) skin involvement (acneiform lesions, erythema nodosum, necrotic folliculitis)
(4) ocular involvement (retinal vasculitis, anterior or posterior uveitis)
(5) neurological signs
(6) vascular signs (arterial aneurysm, arterial or venous thrombosis)
|
Parameter |
Finding |
Points |
|
recurrent oral apthosis |
< 3 attacks per year |
0 |
|
|
>= 3 attacks per year |
1 |
|
genital ulceration or aphthosis |
absent |
0 |
|
|
present (often with scar) |
1 |
|
skin involvement |
absent |
0 |
|
|
present |
1 |
|
ocular involvement |
absent |
0 |
|
|
present |
1 |
|
neurologic signs |
absent |
0 |
|
|
present (excluding isolated headache) |
1 |
|
vascular signs |
absent |
0 |
|
|
present |
1 |
score =
= SUM(points for all 6 parameters)
Interpretation:
• minimum score: 0
• maximum score: 6
• A score >= 3 identified a patient with pediatric Behcet’s disease.
Specialty: Immunology/Rheumatology
