The American Society of Clinical Oncology (ASCO) has reviewed complications associated with immune checkpoint inhibitor therapy.
Patient selection: aseptic meningitis following therapy with an immune checkpoint inhibitor
Parameters:
(1) clinical signs and symptoms
(2) impact on functional status
|
Clinical Signs/Symptoms
|
Functional Status
|
Grade
|
|
none
|
normal
|
G0
|
|
mild; do not concern patient
|
normal
|
G1
|
|
any cranial nerve problem; moderate headache; concern patient
|
some interference with ADL
|
G2
|
|
severe headache; weakness; gait limitation
|
severe interference with self-care; requires assistance
|
G3/4
|
