Systemic lupus erythematosus (SLE) can be diagnosed by specific clinical criteria.
fixed erythema, flat or raised, over the malar eminences
erythematous raised patches with adherent keratotic scaling and follicular plugging; atrophic scarring may occur
includes oral and nasopharyngeal. observed by physician
nonerosive arthritis involving 2 or more peripheral joints, characterized by tenderness, swelling or effusion
pleuritis or pericarditis, or evidence of pericardial effusion
proteinuria (> 0.5 g/d, or > 3+) or cellular casts
seizures without other cause or psychosis without other cause
hemolytic anemia, leukopenia (< 4,000 per µL), lymphopenia (< 1,500 per µL) or thrombocytopenia (< 100,000 per µL), in the absence of a causative drug
positive LE cell preparation, anti-ds DNA antibody, anti-Sm antibodies, false positive VDRL
abnormal ANA titer at any point of time in the absence of drugs known to induce ANA
• If four or more criteria are present at any time during the course of the disease, then a diagnosis of SLE can be made.
• The specificity is 98% and sensitivity 97%.
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Purpose: To diagnose Systemic Lupus Erythematosus (SLE) using the 1982 ACR criteria.
Objective: criteria for diagnosis