Mazeh et al developed a nomogram which can be used during surgery to determine if another hyperfunctioning parathyroid gland is present. This can be used in conjunction with the change in serum parathyroid hormone levels to determine if surgery needs to be continued. The authors are from the University of Wisconsin.
Parameters:
(1) preoperative serum calcium in mg/dL
(2) preoperative serum parathyroid hormone (PTH) in pg/dL
(3) parathyroid gland weight in milligrams
Wisconsin index =
= (preoperative serum calcium) * (preoperative serum PTH)
Index |
Risk Group |
<= 800 |
low |
801 to 1600 |
intermediated |
> 1600 |
high |
The percent of patients with another enlarged parathyroid gland can be estimated from a plot of the parathyroid gland weight and risk group (Figure 5, page 140). The curves can be approximated by.
Risk Group |
Gland Wgt |
Percent with Another Enlarged Parathyroid Gland |
low |
100 to 400 |
139.7 - (0.6753 * (weight)) + (0.000908 * ((weight)^2)) |
low |
400 to 1,000 |
30.09 - (0.04934 * (weight)) + (0.000020 * ((weight)^2)) |
intermediate |
100 to 600 |
124.4 - (0.3465 * (weight)) + (0.000273 * ((weight)^2)) |
intermedate |
600 to 1,000 |
24.47 - (0.02075 * (weight)) |
high |
100 to 400 |
119.7 - (0.2362 * (weight)) + (0.000273 * ((weight)^2)) |
high |
400 to 1,000 |
87.42 - (0.03392 * (weight)) - (0.000034 * ((weight)^2)) |
Specialty: Endocrinology, Clinical Laboratory, Surgery, orthopedic
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