DeRemee et al developed a simple classification for clinical organ involvement in patients with Wegener's granulomatosis. The authors are from the Mayo Clinic in Rochester.
Organ
Code
ENT (ear, nose, throat, upper airway)
E
lung
L
kidneys
K
These may used alone (except for kidney involvement) in the various combinations of 2 or 3 organs. Necrotizing glomerulonephritis alone (K) is not considered specific for Wegener's granulomatosis.
Possible combinations:
(1) E
(2) L
(3) EK
(4) EL
(5) LK
(6) ELK
Midline granuloma pattern: E
Limited patterns: L, EL
Classic patterns: EK, LK, ELK
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