Scheltens et al described a visual rating scale for atrophy of the medial temporal lobe. This is less time consuming to perform than performing volumetry of the hippocampus.
MRI Imaging: midsagittal T1 weighted images
Parameters:
(1) width of the choroid fissure
(2) width of the temporal horn
(3) height of the hippocampal formation
Width of Choroid Fissure
Width of Temporal Horn
Height of Hippocampal Formation
Score
normal
normal
normal
0
mild increase
normal
normal
1
moderate increase
mild increase
mild decrease
2
marked increase
moderate increase
moderate decrease
3
marked increase
marked increase
marked decrease
4
Interpretation:
• The absence of significant atrophy is against the diagnosis of Alzheimer's disease.
• The presence of significant atrophy can identify a patient with mild cognitive impairment who is likely to progress to Alzheimer's disease.
To read more or access our algorithms and calculators, please log in or register.
