Definitions for cutaneous foci of T-cell lymphoma:
(1) patch: visible but not palpable; histology shows eczematous patchy and scattered lymphocytes in papillary dermis
(2) plaque: palpable; histology shows a bandlike infiltrate filling the papillary dermis
(3) tumor: nodular, either exophytic or subcutaneous; histology shows a nodular infiltrate of lymphocytes involving the papillary and reticular dermis with extension into the subcutaneous tissue
|
Parameter
|
Finding
|
Points
|
|
patches
|
<= 30% BSA
|
0
|
|
|
> 30% BSA
|
1
|
|
plaques
|
absent
|
0
|
|
|
present
|
1
|
|
tumors
|
absent
|
0
|
|
|
present
|
1
|
tumor burden index =
= (2 * (points for patches)) + (2 * (points for plaques)) + (1.3 * (points for tumors)) + 1
Interpretation:
• possible indices: 1, 2.3, 3, 4.3, 5 and 6.3
|
Tumor Burden Index
|
10 Year Survival
|
|
1 or 2.3
|
100%
|
|
3
|
64%
|
|
4.3, 5 or 6
|
27%
|
Other prognostic factors identified:
(1) Males tend to have a better prognosis than women.
(2) Age of onset and age at diagnosis did not correlate with prognosis.
