Transplant Risk Score of Bacigalupo et al for a Patient with Primary Myelofibrosis Undergoing Allogeneic Hemopoietic Stem Cell Transplant (HSCT)

Description

Bacigalupo et al developed a risk score for patients with primary myelofibrosis undergoing allogeneic hemopoietic stem cell transplant (HSCT). This can help to identify patients who may benefit from more aggressive management. The authors are from multiple institutions in Italy.

Patient selection: primary myelofibrosis

Parameters:

(1) transfusion history

(2) spleen size in centimeters

(3) donor type

Parameter	Finding	Points
transfusion history	<= 20 units RBCs	0
	> 20 units	1
spleen size	<= 22 cm	0
	> 22 cm	1
donor type	HLA-identical sibling	0
	other (alternative)	1

total score =

= SUM(points for all 3 parameters)

Interpretation:

• minimum score: 0

• maximum score: 3

• The higher the score the greater the risk.

Score	Risk Group	5-Year Survival
0 or 1	low	77%
2 or 3	high	8%

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Description

Specialty

ICD-10