Thrombolytic Predictive Instrument of Selker et al for Intracranial Hemorrhage

 

Parameters:

(1) age

(2) excess pulse pressure

 

Parameter	Finding	Value
age	< 35 years	0
	35 - 75 years	(age in years) - 35
	> 75	40
excess pulse pressure	systolic BP <= 120 mm Hg	0
	(systolic BP) - (diastolic BP) <= 40 mm Hg	0
	criteria A (below)	((systolic BP) - (diastolic BP) - 40) * ((systolic BP) - 120) / 5
	criteria B (below)	35
	criteria C (below)	((systolic BP) - (diastolic BP) - 40)
	criteria D (below)	35

 

where:

• excess pulse pressure = (systolic blood pressure) - (diastolic blood pressure)

• If the diastolic blood pressure is >= 65 mm Hg, the actual value is used. If < 65 mm Hg, the value is set to 65.

 

criteria A

systolic BP > 120 and < 125, AND

(systolic BP) - (diastolic BP) > 40 mm Hg

 

criteria B

systolic BP > 120 and < 125, AND

((systolic BP) - (diastolic BP) - 40) * ((systolic BP) - 120) / 5 > 35

 

criteria C

systolic BP >= 125, AND

(systolic BP) - (diastolic BP) > 40 mm Hg and <= 75

 

criteria D

systolic BP >= 125, AND

(systolic BP) - (diastolic BP) > 75 mm Hg

 

score =

= (0.0591 * (value for patient's age)) + (0.0729 * (value for excess pulse blood pressure)) - 7.7784

 

probability of intracranial hemorrhage =

= 1 / (1 + EXP((-1) * (score)))