The Follicular Lymphoma International Prognostic Index (FLIPI) was developed for determining prognosis in a patient with follicular lymphoma. This is related to the International Prognostic Index for non-Hodgkin's lymphoma.
Parameters:
(1) age of the patient in years
(2) Ann Arbor stage of the lymphoma
(3) serum LDH
(4) hemoglobin
(5) number of involved nodal sites
Parameter
Finding
Points
age in years
< 60 years
0
>= 60 years
1
Ann Arbor stage
I or II
0
III or IV
1
serum LDH
<= upper limit of normal
0
> upper limit of normal
1
hemoglobin
>= 12 g/dL
0
< 12 g/dL
1
number of involved nodal sites
<= 5
0
> 5
1
FLIPI =
= SUM(points for all 5 parameters)
Interpretation:
• minimum index: 0
• maximum index: 5
• The higher the index the more aggressive the disease and the worse the prognosis/
FLIPI
Prognosis
Overall Survival at 5 Years
0 or 1
good
88%
2
intermediate
78%
3 to 5
poor
55%
from Figure in Leonard
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