Soler-Cataluna et al modified the BODE (Body Mass Index, Obstructive Airflow, Dyspnea, Exercise Capacity) Index for patients with chronic obstructive pulmonary disease. The authors are from Hospital General de Requena, Centro de Salud de Lliria, and Hospital La Fe in Valencia, Spain.
The e-BODE index adds acute exacerbations to the original BODE index as a fifth parameter.
Patient selection: male with COPD, stable without exacerbation in the past month
Parameters:
(1) body mass index [BMI = (kilograms body weight) / ((height in meters)^2)]
(2) FEV1 as percent of predicted
(3) dyspnea, measured using the MRC dyspnea scale
(4) exercise capacity as measured by a 6-minute walk
(5) severe exacerbations requiring ED visit or hospital admission (AECOPD) in past year
Parameters |
Finding |
Points |
BMI |
> 21 kg per square meter |
0 |
|
<= 21 kg per square meter |
1 |
FEV1 as percent of predicted |
>= 65% |
0 |
|
50 - 64.9% |
1 |
|
36 - 49.9% |
2 |
|
< 36% |
3 |
MRC dyspnea scale |
0 (none) |
0 |
|
1 |
0 |
|
2 |
1 |
|
3 |
2 |
|
4 (too breathless to leave the house, or breathless when changing clothes) |
3 |
distance walked in 6 minutes |
>= 350 meters |
0 |
|
250 - 349.9 meters |
1 |
|
150 - 249.9 meters |
2 |
|
< 150 meters |
3 |
exacerbations in past year |
none |
0 |
|
1 or 2 |
1 |
|
3 or more |
2 |
total e-BODE index =
= SUM(points for all 5 parameters)
Interpretation:
• minimum index: 0
• maximum index: 12
• The higher the index the worse the prognosis.
Score |
Quartile |
5-Year Survival |
0 to 2 |
1 |
86% |
3 or 4 |
2 |
71% |
5 or 6 |
3 |
55% |
7 to 12 |
4 |
25% |
after Figure 1, page 696
Performance:
• The area under the ROC curve was 0.77.
Specialty: Pulmonology