Younge et al developed a formula for predicting the likelihood of having a positive temporal artery biopsy associated with temporal (giant cell) arteritis. The authors are from the Mayo Clinic.
Parameters:
(1) headache
(2) jaw claudication
(3) scalp tenderness
(4) ischemic optic neuropathy
(5) ESR in mm/h
(6) age in years
|
Parameter |
Finding |
Points |
|
headache |
absent |
0 |
|
|
present |
1 |
|
jaw claudication |
absent |
0 |
|
|
present |
1 |
|
scalp tenderness |
absent |
0 |
|
|
present |
1 |
|
ischemic optic retinopathy |
absent |
0 |
|
|
present |
1 |
X =
= ((age in years) + (48 * (points for headache)) + (108 * (points for jaw claudication)) + (56 * (points for scalp tenderness)) + (70 * (points for ischemic optic retinopathy)) + (ESR) -240) / 50
probability of having a positive temporal biopsy =
= 1 / (1 + EXP((-1) * X))
|
Probability |
Risk Group |
|
< 10% |
low |
|
10 - 80% |
intermediate |
|
> 80% |
high |
Limitations:
• A false negative biopsy may occur if an inadequate biopsy is taken.
Purpose: To evaluate a patient for the likelihood of a positive temporal artery biopsy using the score of Younge et al.
Specialty: Immunology/Rheumatology
Objective: risk factors, prevention
ICD-10: M31.5, M3.6,
