Mlynek et al scored several clinical findings in a patient being treated for chronic urticaria. This can be used to monitor the patient to determine the effectiveness of therapy. The authors are from Charite-Universitatsmedizin Berlin, Medical Uniersity Lodz (Poland), and University Hospital Mainz.
Patient selection: chronic urticaria
Parameters:
(1) number of wheals and erythemas
(2) pruritis (itching)
(3) duration per day
(4) size of largest skin lesion in cm
(5) number of angioedemas per day
Parameter |
Finding |
Points |
---|---|---|
number of wheals |
0 (none) |
0 |
|
1 to 9 (mild) |
1 |
|
10 to 50 (moderate) |
2 |
|
> 50 (severe) |
3 |
pruritis severity |
none |
0 |
|
mild |
1 |
|
moderate |
2 |
|
severe |
3 |
duration of symptoms |
none |
0 |
|
< 1 hour per day |
1 |
|
1 to 3 hours per day |
2 |
|
> 3 hours per day |
3 |
size of largest skin lesion |
none |
0 |
|
< 1 cm |
1 |
|
1 to 3 cm |
2 |
|
> 3 cm |
3 |
number of angioedemas |
none |
0 |
|
1 per day |
1 |
|
2 or 3 per day |
2 |
|
4 or more per day |
3 |
where:
• The number wheals and severity of pruritis are features of the daily urticaria activity score (UAS).
total daily score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum total score: 0
• maximum total score: 15
• The number of items at each level (none, mild, moderate, severe) can also be recorded.
Purpose: To evaluate a patient with chronic urticaria based on the daily severity of 5 findings as reported by Mlynek et al.
Specialty: Immunology/Rheumatology, Dermatology
Objective: clinical diagnosis, including family history for genetics, severity, prognosis, stage
ICD-10: L50,