Acute Renal Failure Mortality Score

Scores:

(1) at onset = 0 hours (SHARF0)

(2) at 48 hours after admission (SHARF48)

Parameters:

(1) age (mean age for study patients 70 years)

(2) serum albumin in g/L

(3) prothrombin time in percent activity

(4) mechanical ventilation

(5) heart failure

where:

• The prothrombin time in percent is determined by taking normal plasma and diluting it with coagulation factor deficient plasma. The aPTT is measured for each dilution and a plot is made. A patient's PTT is then done and the corresponding percent prothrombin activity is read off the plot.

SHARF at 0 hour =

= (7 * (points for age)) + (6 * (points for serum albumin)) + (3 * (points for percent prothrombin time)) + (39 * (points for mechanical ventilation at onset)) + (9 * (points for heart failure at onset)) + 52

SHARF at 48 hours =

= (7 * (points for age)) + (6 * (points for serum albumin)) + (3 * (points for percent prothrombin time)) + (43 * (points for mechanical ventilation at 48 hours)) + (16 * (points for heart failure at 48 hours)) + 52

Interpretation:

• minimum score for SHARF0 and SHARF48: 61

• maximum score for SHARF0: around 229

• maximum score for SHARF48: around 240

• According to Figure 1 (page 14) the hospital mortality can be estimated from the scores.