The Spanish MRI (S-MRI) was developed to describe bone marrow involvement for a patient with Gaucher's disease based on the MRI findings.
Sites examined:
(1) vertebrae
(2) pelvis
(3) both femurs
Parameters:
(1) MRI pattern
(2) complications at site (avascular necrosis, bone infarct, collapse)
|
Parameter
|
Finding
|
Points
|
|
MRI patterns
|
normal (N)
|
0
|
|
|
nonhomogeneous reticular (NHR)
|
1
|
|
|
nonhomogeneous mottled (NHM)
|
2
|
|
|
nonhomogeneous diffuse (NHD)
|
3
|
|
|
homogeneous (H)
|
4
|
|
complications
|
absent
|
0
|
|
|
present
|
4
|
subscore for each site =
= SUM(points for the 2 parameters)
total S-MRI =
= SUM(points for all 3 sites)
Interpretation:
• minimum subscore: 0
• maximum subscore: 8
• minimum total score: 0
• maximum total score: 24
• The higher the score the more severe the bone marrow involvement.
