The SOMA (Subjective, Objective, Management, Analytic) – LENT (Late Effects of Normal Tissue) scoring system can be used to a woman for ovarian or reproductive complications following radiation and chemotherapy.
Subjective measures:
(1) hot flashes
(2) dysmenorrhea
(3) menstruation
Objective measures:
(1) ovulation
(2) involuntary infertility
(3) osteoporosis
Management measures:
(1) dysmenorrhea and/or hot flashes
(2) menstruation
(3) osteoporosis
Analytic studies:
(1) FSH, LH and estradiol levels: assessment of hormonal production
(2) bone densitometry: quantify bone density
If no toxicity is present, then the 0 points are assigned.
If a toxicity is present, then the grade indicates the number of points to assign.
|
|
Grade 1 |
Grade 2 |
Grade 3 |
Grade 4 |
|
hot flashes |
occasional |
intermittent |
persistent |
NA |
|
dysmenorrhea |
occasional |
intermittent |
persistent |
NA |
|
menstruation |
NA |
oligomenorrhea |
amenorrhea |
NA |
|
ovulation |
NA |
NA |
anovulation in premenopausal woman |
NA |
|
involuntary infertility |
NA |
NA |
infertility |
NA |
|
osteoporosis |
NA |
NA |
radiographic evidence |
fracture |
|
management of dysmenorrhea or hot flashes |
NA |
hormone replacement |
NA |
NA |
|
management of menstruation |
NA |
hormone replacement |
NA |
NA |
|
management of osteoporosis |
NA |
hormone replacement, calcium supplements |
NA |
NA |
total score =
= SUM(points for all 9 items)
LENT score =
= (total score) / 9
Interpretation:
• maximum total score: 25
• minimum LENT score: 0
• maximum LENT score: 2.78
Specialty: Hematology Oncology, Obstetrics & Gynecology
