Clinical Features of Nociceptive Central Pain

 

Peripheral nociceptive injury involves damage to peripheral nociceptive nerve endings and can be seen with:

(1) small fiber neuropathy

(2) radiculopathy

(3) plexopathy (brachial, lumbosacral)

(4) complex regional pain syndrome

(5) inflammatory peripheral neuropathy

 

Clinical findings seen with nociceptive central pain:

(1) hypersensitivity to stimuli at the site of injury

(2) mechanoallodynia (pain triggered by a mechanical stimulus)

(3) thermal hyperalgesia

(4) hyperpathia

(5) extraterritoriality with regional distribution of pain (in complex regional pain syndrome or reflex sympathetic dystrophy)

(6) neurogenic inflammation inflammation, autonomic dysregulation, and/or motor phenomenona (in complex regional pain syndrome or reflex sympathetic dystrophy)