The amount of a particular segmental imbalance may be expressed as the fraction of the haploid autosomal length (HAL). This can be calculated from the segment's relative length, the involved chromosome's relative length, and the chromosome's percent of the HAL.
Autosomes: The 22 pairs of non-sex (non-X, non-Y) chromosomes in the human genome.
Haploid: A single set of the 22 chromosomes.
Haploid Autosomal Length: Sum of the chromosomal lengths.
chromosome length as percentage of HAL =
= (length of chromosome) / (total HAL) * 100%
|
Chromosome
|
Percent of HAL
|
|
1
|
8.44%
|
|
2
|
8.02%
|
|
3
|
6.83%
|
|
4
|
6.30%
|
|
5
|
6.08%
|
|
6
|
5.90%
|
|
7
|
5.36%
|
|
8
|
4.93%
|
|
9
|
4.80%
|
|
10
|
4.59%
|
|
11
|
4.61%
|
|
12
|
4.66%
|
|
13
|
3.74%
|
|
14
|
3.56%
|
|
15
|
3.46%
|
|
16
|
3.36%
|
|
17
|
3.25%
|
|
18
|
2.93%
|
|
19
|
2.67%
|
|
20
|
2.56%
|
|
21
|
1.90%
|
|
22
|
2.04%
|
|
total
|
100%
|
segment as percent of chromosome =
= (relative length of segment) / (relative length of chromosome) * 100%
segment as percent of HAL =
= (segment as percent of chromosome) * (chromosome length as percent of HAL)
The relative lengths can be measured using ideograms of the chromosomes (Francke, 1994; Gardner and Sutherland, 1996).
