Kaminski et al developed a score for identifying an adult with advanced colorectal carcinoma detected at the time of colonoscopy. The authors are from the Maria Sklodowska-Curie Memorial Cancer Centre, Institute of Oncology and the Medical Centre of Postgraduate Education in Warsaw, Poland.
Patient selection: asymptomatic Caucasian adult from 40 to 66 years undergoing screening colonoscopy
Advanced colorectal neoplasia was defined as cancer OR polyp with significant features (diameter >= 10 mm, villous, tubulovillous, high grade dysplasia)
Parameters:
(1) age in years
(2) family history of colorectal canc
(3) gender
(4) smoking history in pack years
(5) body mass index in kg per square meter
|
Parameter |
Finding |
Points |
|
age in years |
40 to 49 years |
0 |
|
|
50 to 54 years |
1 |
|
|
55 to 59 years |
2 |
|
|
60 to 66 years |
3 |
|
family history of CRC |
none |
0 |
|
|
1 first degree relative, diagnosis >= 60 years |
1 |
|
|
1 first degree relative, diagnosis < 60 years |
2 |
|
|
2 or more first degree relatives |
2 |
|
gender |
female |
0 |
|
|
male |
2 |
|
smoking history |
none |
0 |
|
|
< 10 pack years |
0 |
|
|
>= 10 pack years |
1 |
|
body mass index |
< 30 kg per sq m |
0 |
|
|
>= 30 and male |
0 |
|
|
>= 30 and female |
1 |
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 8
• The higher the score the greater the risk of colorectal cancer.
|
Score |
Percent with Advanced Neoplasia |
|
0 |
1.3% |
|
1 |
4.2% |
|
2 |
4.6% |
|
3 |
6.1% |
|
4 |
7.7% |
|
5 |
11.3% |
|
6 |
13.7% |
|
7 or 8 |
19.1% |
Specialty: Gastroenterology
