RTOG/EORTC Criteria for Mucous Membrane Complications to Irradiation

Description

The Radiation Therapy Oncology Group (RTOG) and the European Organization for Research on the Treatment of Cancer (EORTC) provide criteria for assessing the complications of radiation therapy affecting the mucous membranes.

Guidelines

(1) Change in affected parameter is ascribed to radiation therapy and not underlying or concurrent disease.

(2) Considered acute if occurs from day 1 to 90; after day 90 considered late complication.

Acute Complications

Grade 0: none (no change from baseline)

Injury	Grade 1	Grade 2	Grade 3	Grade 4
mucosa	injection	patchy mucositis	confluent fibrinous mucositis	NA
pain	mild pain not requiring analgesics	moderate pain requiring analgesics	severe pain requiring analgesics	NA
other	NA	may show an inflammatory serosanguinous discharge	NA	ulceration, hemorrhage, necrosis

Grade 5: death directly due to radiation effect

Late Complications

Grade 0: no change from baseline

Injury	Grade 1	Grade 2	Grade 3	Grade 4
atrophy	slight	moderate	marked	NA
dryness	slight	moderate with little mucus	complete	NA
telangiectasia	NA	moderate	gross	NA
other	NA	NA	NA	ulceration

Grade 5: death directly due to radiation late effect

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Description

Specialty

ICD-10