Description

Krumholz et al developed a model for predicting the one-year mortality rate for an adult >= 65 years of age following an acute myocardial infarction (AMI). This can help to identify a patient who may benefit from more aggressive management. The authors are from Yale University (New Haven) and Qualidigm (Middletown, Connecticut).


 

NOTE: Another risk model by Krumholz for elderly AMI patients (dealing with in-hospital mortality) is reported in 06.08.22.

 

Patient selection: adults >= 65 years of age with AMI

 

Outcome: 1 year mortality after the AMI

 

Parameters:

(1) peripheral vascular disease

(2) age of the patient in years

(3) body mass index (BMI)

(4) urinary incontinence or no urinary output

(5) walking ability with and without assistance

(6) left ventricular ejection fraction (LVEF) in percent

(7) heart failure or cardiomegaly diagnosed prior to discharge

(8) renal dysfunction (serum creatinine > 2.5 mg/dL or BUN > 40 mg/dL)

 

Parameter

Finding

Points

peripheral vascular disease

absent

0

 

present

1

age of the patient

65 to 74 years

0

 

75 to 84 years

1

 

>= 85 years

2

body mass index

< 20 kg per meter squared

1

 

>= 20 kg per meter squared

0

urinary incontinence or no urine output

no

0

 

yes

1

walking

does not require assistance

0

 

requires assistance

1

 

unable to walk

2

LVEF

< 20%

3

 

20 to 40%

2

 

> 40%

0

heart failure or cardiomegaly

no

0

 

yes

2

renal dysfunction

no

0

 

yes

2

 

where:

• One item describes urinary incontinence or no urinary output. Another mentions renal dysfunction. The absence of urinary output might imply renal dysfunction.

 

risk score =

= SUM(points for all 8 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 14 (maximum observed in study 13)

• The higher the score the greater the risk of 1 year mortality.

 

Total Score

1 Year Mortality Rate

0 to 2

low risk

3 to 5

moderate risk

>= 6

high risk

 


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