The Berlin-Frankfurt-Munster (BFM) Group classified patients with Burkitt's lymphoma into 4 risk groups.
Parameters:
(1) St. Jude Stage or Burkitt's Acute Leukemia (B-AL, or L3-AL)
(2) complete resection
(3) serum LDH in U/L
(4) CNS involvement
|
Stage |
Resection |
LDH |
CNS |
Group |
|
I or II |
complete |
NA |
NA |
R1 |
|
I or II |
incomplete |
NA |
NA |
R2 |
|
III |
NA |
< 500 |
NA |
R2 |
|
III |
NA |
500 - 999 |
NA |
R3 |
|
III |
NA |
>= 1,000 |
NA |
R4 |
|
IV or B-AL |
NA |
< 1,000 |
No |
R3 |
|
IV or B-AL |
NA |
< 1,000 |
Yes |
R4 |
|
IV or B-AL |
NA |
>= 1,000 |
No |
R4 |
|
IV or B-AL |
NA |
>= 1,000 |
Yes |
R4 |
Limitations:
• The method for determining serum LDH must match that of the BFM Group.
Specialty: Hematology Oncology
