Walton et al identified patients with malaria who are at risk for multiple organ dysfunction syndrome (MODS) based on laboratory findings at the time of hospital admission. The authors are from the University of Michigan, Central Military Hospital Bogota, and University of La Sabana in Chia, Columbia.
Patient selection: adult with malaria admitted to a hospital in Columbia
Outcome: multiple organ dysfunction syndrome (MODS)
Parameters on hospital admission:
(1) level of parasitemia (number per microliter)
(2) hemoglobin in g/dL
Parasitemia (per microliter)
Hemoglobin
MODS
2-770
> 11 g/dL
0%
8.6 to 11.0 g/dL
6%
<= 8.5 g/dL
0%
771-2,965
> 11 g/dL
4%
8.6 to 11.0 g/dL
9%
<= 8.5 g/dL
25%
2,966-7,220
> 11 g/dL
2%
8.6 to 11.0 g/dL
18%
<= 8.5 g/dL
43%
> 7,220
> 11 g/dL
6%
8.6 to 11.0 g/dL
40%
<= 8.5 g/dL
56%
Limitations:
• The level of immunity affects response to an infection.
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