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Risk Factors of Walker and Jick for Bleeding During Heparin Therapy

Purpose: To identify a patient at risk for bleeding associated with heparin therapy using the risk factors of Walker and Jick.

Description

Walker and Jick identified risk factors associated with bleeding during heparin therapy. This can help identify patients who may require closer monitoring during heparin therapy or a reduced heparin dose. The authors are from Boston University Medical Center.


Parameters associated with major bleeding:

(1) female gender

(2) age >= 40 years of age (greater if >= 60 years)

(3) BUN >= 50 mg/dL

(4) heavy alcohol use (binge drinker or > 5 alcoholic drinks per day)

(5) heparin dose >= 100 U/kg

(6) aspirin use

(7) substantial underlying morbidity (as evidenced by death during the admission from causes other than hemorrhage)

 

Parameters associated with mild or moderate bleeding:

(1) female gender

(2) heparin dose >= 50 U/kg

(3) aspirin use

(4) substantial underlying morbidity


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Specialty

Objective

ICD-10