Pedros et al identified risk factors for hospital admission because of adverse drug reaction (ADR). The authors are from Bellvitge University Hospital, L'Hospitalet de Llobregat, and University of Barcelona in Spain.
Patient selection: hospital admission for adverse drug reaction (ADR)
Frequency: 4% of urgent admissions
Risk factors:
(1) age
(2) number of drugs being taken at the time of hospital admission
Parameter |
Findings |
Odds Ratio |
age |
< 65 years |
1 |
|
>= 65 |
1.6 |
number of drugs |
<= 2 |
1 |
|
3 to 5 |
5.1 |
|
6 to 9 |
5.9 |
|
>= 10 |
8.9 |
Reason for Admission |
Implicated Drug |
acute renal failure |
renin-angiotensin system inhibitors, NSAID, other |
gastrointestinal hemorrhage |
anticoagulant, NSAID or antiplatelet drug |
other hemorrhage |
anticoagulant |
decreased level of consciousness |
benzodiazepines, neuroleptics |
atrioventricular block |
calcium channel blocker, beta-blocker |
Specialty: Toxicology, Emergency Medicine, Critical Care
ICD-10: ,