Mazeika et al identified factors in patients with diabetes mellitus that are associated with restenosis of a coronary artery after a percutaneous intervention. This can help identify those patients who may require closer monitoring and more aggressive monitoring. The authors are from The Toronto Hospital in Canada.
Parameters associated with an increased risk of angiographic restenosis in a diabetic as independent risk factors:
(1) poor glycemic control (glycosylated hemoglobin level > 8%)
(2) small vessel diameter (< 2.87 mm)
(3) use of balloon angioplasty without stent (benefit of stents not seen in small vessels)
where:
• I assume the blood vessel diameter refers to the luminal diameter, since data was collected from angiography.
Parameter
Odds Ratio
95% CI
p value
poor glycemic control
3.03
1.06 - 8.65
0.038
small vessel diameter
3.41
1.17-9.95
0.025
balloon without stent
3.12
1.08-9.00
0.036
from Table IV, page 1018
These findings underlie the need for good glycemic control in diabetics with coronary artery disease.
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