Mahmud et al identified risk factors that can help identify a patient at risk for periprocedural myocardial infarction (PPMI) after a percutaneous coronary intervention (PCI). This can help identify a patient who may require closer monitoring or more aggressive therapy. The authors are from the University of California at San Diego.
Parameters:
(1) reflow or TIMI grade
(2) residual stenosis in culprit vessel
(3) closure of sidebranches
(4) chest pain
(5) hypotension
(6) electrocardiographic (ECG) changes
(7) use of GP IIb/IIIa inhibitor for bailout
(8) intervention involving saphenous vein graft (SVG)
(9) intracoronary artery thrombus
(10) procedural events
PPMI not expected (unlikely) – all of the following:
(1) reflow or TIMI grade after the procedure: TIMI grade 3
(2) residual stenosis in culprit vessel: < 50%
(3) closure of sidebranches: none in major or minor sidebranches
(4) chest pain: not prolonged (<= 5 minutes and resolved by end of procedure)
(5) hypotension: not prolonged (<= 5 minutes and resolved by end of procedure)
(6) electrocardiographic (ECG) changes: not prolonged (<= 5 minutes and resolved by end of procedure)
(7) use of GP IIb/IIIa inhibitor for bailout: no
(8) intervention involving savenous vein graft (SVG): none
(9) intracoronary artery thrombus: none visualized
(10) procedural events: uneventful
PPMI not unexpected (possible):
(1) reflow or TIMI grade after the procedure: TIMI grade 3
(2) residual stenosis in culprit vessel: < 50%
and one or more of the following:
(1) transient no reflow or slow reflow
(2) transient closure of culprit vessel
(3) closure of sidebranches: loss of a minor sidebranch (< 1.5 mm); transient closure of major sidebranch (>= 1.5 mm)
(4) chest pain: prolonged (> 5 minutes and resolved by end of procedure)
(5) hypotension (> 5 minutes and resolved by end of procedure)
(6) electrocardiographic (ECG) changes (> 5 minutes and resolved by end of procedure)
(7) use of GP IIb/IIIa inhibitor for bailout
(8) intervention involving savenous vein graft (SVG): present
(9) intracoronary artery thrombus: visualized without clinical evidence of distal embolization
(10) procedural events: minor complication
PPMI not unexpected (possible) – both of the following:
(1) reflow or TIMI grade after the procedure: TIMI grade 3
(2) residual stenosis in culprit vessel: >= 50%
PPMI expected (probable) – one or more of the following:
(1) reflow or TIMI grade after the procedure: no reflow or TIMI grade 0-2 at the end of the procedure
(3) closure of sidebranches: loss of major sidebranch (>= 1.5 mm)
(4) chest pain: unresolved
(5) hypotension: unresolved with systolic blood pressure < 80 mm Hg
(6) electrocardiographic (ECG) changes: prolonged
(9) intracoronary artery thrombus: visualized with clinical evidence of distal embolization
(10) procedural events: major complication
where:
• Intracoronary thrombus in the expected group was not listed in the original table, but seems reasonable based on the definition in the not unexpected group.
Specialty: Cardiology
ICD-10: ,