Patient selection: >= 65 years of age
Administration of oral sodium phosphate may result in:
(1) hyperphosphatemia
(2) hypernatremia
(3) hyperchloremia
(4) hypokalemia
(5) hypocalcemia
Risk factors for developing hyperphosphatemia and electrolyte abnormalities:
(1) renal insufficiency (with reduced creatinine clearance and impaired potassium conservation)
(2) frail and dependent
(3) cognitive impairment (dementia)
(4) pre-existing hypocalcemia, hypokalemia or hyperphosphatemia
A patient with pre-existing cardiovascular disease may be at greater risk for complications if electrolyte abnormalities develop.
A patient with one or more risk factors should be carefully evaluated before and after use of oral sodium phosphate:
(1) measurement of serum creatinine and calculation of creatinine clearance
(2) monitoring of serum phosphorus, sodium, calcium and potassium
