Uterine fibroids are common benign tumors of the myometrium. A number of risk factors may impact the number and size of the these lesions.
Parameter |
Increased Risk |
Decreased Risk |
pregnancies lasting >= 20 weeks (parous) |
0 (nulliparous) |
>= 6 |
age and menstrual status |
>= 40 years |
postmenopausal without HRT |
family history of uterine fibroids |
present |
NA |
body weight |
obesity |
below 55 kg |
cigarette smoking |
NA |
pack per day |
race |
Black |
NA |
oral contraceptives |
NA |
prolonged use, use of Depo-Provera |
where:
• Parity indicates the number of pregnancies lasting 20+ weeks (Stewart, 2001).
• Depo-Provera = depot medroxyprogesterone acetate
• HRT = hormone replacement therapy
According to Ross et al, many of the factors associated with increased risk represent conditions of unopposed estrogen exposure.
Specialty: Obstetrics & Gynecology
ICD-10: ,