Gestational age in weeks at birth - recommended screening if <= 28 weeks.
(1) The Royal College of Ophthalmologists recommended screening if gestational age is < 32 weeks (<= 31 weeks)
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Gestational Age
|
Percent of Neonates Who Develop ROP
|
|
< 28 weeks
|
> 80%
|
|
28 - 31 weeks
|
60%
|
Birthweight in grams - recommended screening if <= 1,500 grams:
(1) more serious stages of ROP were associated with birthweight < 1,200 grams
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Birthweight
|
Percent of Neonates Who Develop ROP
|
|
< 750 grams
|
90%
|
|
750 - 999 grams
|
78%
|
|
1,000 - 1,250 grams
|
47%
|
Neonatal risk factors: may be associated with ROP even if > 32 week gestational age and birthweight > 1,500 grams:
(1) a sick neonate with an unstable clinical course
(2) bronchopulmonary dysplasia
(3) multiple births (usually associated with small birthweight and early delivery)
(4) administered supplemental oxygen (screen if birthweight <= 1,800 grams)
(5) hemorrhagic shock from placental abruption, etc.
Maternal risk factors:
(1) essential hypertension prior to pregnancy
Racial factors:
(1) Afro-Americans have a 2-fold reduction in risk of progressing to severe disease
