Description

The Reversible Cerebral Vasoconstriction Syndrome (RCVS) may be diagnosed if certain findings are present. It must be distinguished from other conditions, especially a cerebral vasculitis.


 

Conditions that may be associated with RCVS:

(1) benign angiopathy of the CNS (BACNS)

(2) Call-Fleming syndrome

(3) postpartum angiopathy

(4) migrainous vasospasm

(5) drug-induced pseudoarteritis

(6) pheochromocytoma

 

Features of conditions with RCVS:

(1) usual onset consists of a thunderclap headache with or without associated neurologic deficits

(2) angiographic appearance of vasculitis

(3) reversal of angiographic changes after reversal of underlying cause, usually within 4-12 weeks

(4) relatively benign course

(5) CSF protein and leukocyte count normal or only mildly elevated

 

Exclusions:

(1) aneurysmal subarachnoid hemorrhage

(2) absence of secondary causes of vasculitis

(3) absence of primary angiitis of the CNS (PACNS)

 


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