Barbui and other members of the European LeukemiaNet listed response criteria following therapy for essential thrombocythemia. The authors are from multiple hospitals in Europe participating in the European LeukemiaNet.
Patient selection: primary thrombocythemia following therapy
Parameters:
(1) absolute platelet count AND/OR change in platelet count from baseline
(2) disease-related symptoms
(3) spleen size (on imaging studies)
(4) white blood cell count
Platelet Count
Symptoms
Spenic Size
WBC Count
Response
<= 400,000 per µL
none
normal
<= 10,000 per µL
complete
<= 600,000 per µL OR decrease > 50%
NA
NA
NA
partial
> 600,000 per µL AND decrease <= 50%
NA
NA
NA
none
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