Description

Khan et al identified risk groups for patients undergoing renal replacement therapy. A patient at higher risk may benefit from more aggressive management or treatment with a novel therapy. The authors are from the University of Aberdeen, Aberdeen Royal Infirmary and Ninewells Hospital in Dundee.


 

Patient selection: end-stage renal disease treated by hemodialysis, continuous abdominal peritoneal dialysis or renal transplantation

 

Parameters:

(1) age

(2) comorbid conditions

Age in Years

Comorbid Conditions

Risk Group

> 80 years

NA

high

NA

end stage renal disease plus >= 2 organ dysfunctions

high

NA

diabetes and cardiopulmonary disease

high

NA

visceral malignancy

high

70 to 80 years

NA

medium

< 70 years

diabetes mellitus

medium

< 80 years

>= 1 comorbid conditions (see below)

medium

< 70

none

low

 

where:

• The medium risk group with age < 80 and >= 1 comorbid factor could be rewritten as < 70 and >= 1 comorbid factor since 70-80 already is at medium risk.

• The visceral malignancy probably should only be applied if uncontrolled. Hematologic malignancy should also confer risk.

• Should a patient with multiple medium risk criteria met be bumped up to high risk?

 

Comorbid conditions:

(1) angina

(2) previous myocardial infarction

(3) cardiac failure

(4) chronic obstructive airways disease

(5) pulmonary fibrosis

(6) liver disease (cirrhosis, chronic hepatitis)

 


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