Corpus Cavernosum Electromyography (CC-EMG) can be used to assess smooth muscle activity in a patient with erectile dysfunction (ED). This can detect the smooth muscle relaxation that occurs after papaverine injection into the corpus cavernosum.
Device: CC-EMG module of the Ellipse 4 (Andromeda Germany) with a 2 channel electromyography amplifier and coaxial needle electrodes
Measurements include:
(1) electrical activity of the corpus callosum (EACC) in µv under basal conditions, measured as deflection between positive and negative peaks
(2) EACC 10 minutes after intracavernosal injection of papaverine, 60 to 120 mg
Baseline EACC
Diagnosis
decreased to normal
no autonomic dysfunction, including psychogenic ED
increased
autonomic dysfunction
relaxation degree =
= ((EACC before papaverine) - (EACC after papaverine)) / (EACC before papaverine) * 100%
Relaxation Degree
Diagnosis
>= 80%
normal or psychogenic ED
66%
mild to moderate cavernoocclusive dysfunction
< 50%
severe cavernoocclusive disease
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