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Regression Model of Wells et al for Predicting Warfarin Dose Using Pharmacogenetics

Purpose:

To predict the maintenance dose of warfarin for a patient based on clinical and genetic polymorphisms.

Specialty:

Hematology, Hematology, Clinical Pharmacology, Pharmaceutical Medicine

Objective:

pharmacogenetics, dosage calculations, dosage adjustments

ICD-10:

I80, I81, I82, I83

Description:

Wells et al developed a regression model for predicting the dose of warfarin needed by a patient based on clinical data and genetic polymorphisms. The authors are from the University of Ottawa, Ottawa Hospital Research Institute and Children's Hospital of Eastern Ontario.

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