Description

The United Kingdom Working Group identified diagnostic criteria for atopic dermatitis. They used logistic regression to develop 2 equations for predicting the probability of atopic dermatitis in a patient.


 

Factors most useful diagnostic criteria:

(1) history of flexural dermatitis

(2) visible flexural dermatitis

(3) onset of rash before 2 years of age

(4) rash itchy (pruritic)

(5) history of asthma

(6) history of dry skin

Criterion

Points

absent

0

present

1

 

X =

= (2.4 * (points for history of flexural dermatitis)) + (1.3 * (points for visible flexural dermatitis)) + (3.7 * (points for onset before 2 years of age)) + (1.2 * (points for itchy rash)) + (1.9 * (points for history of asthma)) + (1.3 * (history of dry skin)) - 5.6

 

probability of atopic dermatitis =

= 1 / (1 + EXP((-1) * X))

 

For a pediatric patient < 16 years of age:

 

Y =

= (1.84 * (points for history of flexural dermatitis)) + (2.09 * (points for visible flexural dermatitis)) + (3.46 * (points for onset before 2 years of age)) + (1.71 * (points for itchy rash)) - 4.36

 

Note that a history of asthma and of dry skin are not in the pediatric equation

 

probability of atopic dermatitis =

= 1 / (1 + EXP((-1) * Y))

 


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