A patient with Loeys-Dietz Syndrome (LDS) should exercise but needs to do this with care.
The patient should be evaluated prior to starting an exercise program. Echocardiography of the aorta should be performed initially and at regular intervals. Stability of the cervical spine should be assessed.
The patient can engage in aerobic activities provided that it is done in moderation.
Activities to avoid:
(1) contact sports
(2) competitive sports or sports with requiring significant exertion
(3) isometric exercises
(4) activities that cause joint injury or pain
(5) breathing against resistance if there is a history of pneumothorax
(6) breathing with positive pressure ventilation (SCUBA diving) if there is a history of pneumothorax
Additional things to avoid:
(1) decongestants or other drugs that stimulate the cardiovascular system
(2) exercising alone
(3) exercising in a remote location where access to emergency services may be limited
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