If the elimination rate constant is multiplied by the total amount of drug in the body, the actual rate of elimination at any given time can be determined.
rate of elimination =
= ((elimination rate constant) * (amount of drug in the body)) =
= ((clearance) * (plasma concentration at time T))
This is the general equation for all first order processes and expresses the fact that the rate is proportional to the declining quantity of drug that is present.
To read more or access our algorithms and calculators, please log in or register.
