A serum creatinine of 1 mg/dL corresponds to a creatinine clearance of approximately 100 mg/min. If the daily creatinine production is kept relatively constant, the fraction of normal creatinine clearance is the inverse of the serum creatinine.
estimated creatinine clearance in mL/min =
= (100 / (serum creatinine in mg/dL)) mL/min
Limitations:
• The equation gives reasonable values if aged 25-50 years and weighing 60-80 kilograms.
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