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Anklyosing Spondylitis & Axial Spondyloarthritis | Risk Factors for Radiographic Progression

Purpose: To identify a patient with ankylosing spondylitis (AS) or axial spondyloarthritis (SpA) who is at risk for radiographic progression.

Description

Poddubnyy and Sieper listed risk factors for radiographic progression in patients with ankylosing spondylitis and axial spondyloarthritis. Progression of disease results in reduced spinal mobility and a decline in functional status. The authors are from Charite Universitatsmedizin in Berlin.


 

Patient selection: ankylosing spondylitis (AS) or axial spondyloarthritis (SpA)

 

Outcome: radiographic progression

 

Risk factors for radiographic progression:

(1) syndesmophytes at baseline

(2) elevated acute phase reactants - erythrocyte sedimentation rate (ESR) and/or C-reactive protein (CRP)

(3) smoking

 

Non -radiographic progession of axial spondyloarthritis to ankylosing spondylitis is predicted by an elevated CRP.

 


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Specialty

Objective

ICD-10