Boesken described several patterns of proteinuria based on the concentration of various proteins in the urine.
Parameters:
(1) urine albumin concentration in mg/L
(2) urine IgG in mg/L
(3) urine alpha-1 microglobulin in mg/L
(4) urine creatinine in g/L
ratio of urine albumin to creatinine in mg/L =
= (urine albumin) / (urine creatinine)
ratio of urine IgG to creatinine in mg/L =
= (urine IgG) / (urine creatinine)
ratio of urine alpha-1 microglobulin to creatinine in mg/L =
= (urine alpha-1 microglobulin) / (urine creatinine)
|
Albumin Ratio |
IgG Ratio |
a1MG Ratio |
Type |
|
< 25 |
|
< 14 |
Type 0 |
|
< 25 |
|
>= 14 |
Type IV |
|
>= 25 |
<= 10 |
< 14 |
Type III |
|
>= 25 |
> 10 and < 20 |
< 14 |
Type II |
|
>= 25 |
>= 20 |
< 14 |
Type I |
|
>= 25 |
> 10 |
>= 14 |
Type V |
|
Type |
Pattern of Proteinuria |
|
Type 0 |
physiological |
|
Type IV |
tubular |
|
Type III |
highly selective glomerular |
|
Type II |
selective glomerular |
|
Type I |
unselective glomerular |
|
Type V |
mixed |
Specialty: Nephrology, Clinical Laboratory
