Hasselbalch and Jensen developed a simple prognostic score for patients with idiopathic myelofibrosis. This was developed at the Bispebjerg Hospital in Copenhagen, Denmark.
Parameters: based on data collected at the time of initial diagnosis:
(1) hemoglobin concentration
(2) platelet count
(3) osteomyelosclerosis on skeletal X-rays
(4) spleen size on physical examination
|
Parameter |
Finding |
Points |
|
hemoglobin concentration |
>= 10 g/dL |
0 |
|
|
< 10 g/dL |
1 |
|
platelet count |
>= 100,000 per µL |
0 |
|
|
< 100,000 per µL |
1 |
|
osteomyelosclerosis |
present |
0 |
|
|
absent |
1 |
|
spleen size |
impalpable |
0 |
|
|
palpable |
1 |
prognostic score =
= SUM(points for the 4 parameters)
Interpretation:
• minimum score: 0
• maximum score
• The higher the score, the worse the prognosis
|
Prognostic Score |
Risk Group |
Median Survival |
|
0 or 1 |
low risk |
69 months |
|
2 or 3 |
intermediate risk |
33 months |
|
4 |
high risk |
4 months |
Specialty: Hematology Oncology
ICD-10: ,
