Prognostic Score of Caillard et al for Post-Transplant Lymphoproliferative Disorder (PTLD)

Description

Caillard et al developed a prognostic score for a patient who develops a post-transplant lymphoproliferative disorder (PTLD) following a renal transplant. This can help to identify a patient who may benefit from more aggressive management. The authors are from multiple hospitals in France.

Patient selection: PTLD following renal transplant

Parameters:

(1) age and serum creatinine

(2) serum LDH concentration

(3) type of PTLD

Parameter	Finding	Points
age and serum creatinine	age > 55 years AND serum creatinine > 133 µmol/L	2
	other	0
serum LDH concentration	normal	0
	elevated	1
type of PTLD	monomorphic PTLD	1
	disseminated PTLD	1
	both	2
	other	0

where:

• Having both monomorphic and disseminated PTLD at the same time may be impossible but that is the only way to get the maximum score of 5 given in the paper.

total score =

= SUM(points for all 3 parameters)

Interpretation:

• minimum score: 0

• maximum score: 5

• The higher the score the worse the prognosis.

Total Score	10-Year Overall Survival
0	85%
1	80%
2 or 3	56%
4 or 5	0%

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Prognostic Score of Caillard et al for Post-Transplant Lymphoproliferative Disorder (PTLD)

Description

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