A prognostic score based on four variables can be used to estimate the conception rate within 3 to 5 years for subfertile males.
Parameters:
(1) duration of infertility in years
(2) motility index (Macleod, 1969) = (percent motile sperm from 0 to 100) * (motility grade)
(3) sperm density in millions per mL
(4) age of man in years
where:
• percent motile sperm is normally >= 50%
• motility grade: none = 1, poor = 2, fair = 3, good = 4.
• oligozoospermia is when sperm density is < 20 million per mL; severe oligozoospermia is when the sperm density is <= 10 million per mL
Parameter
Finding
Value
duration of infertility in years
<= 3
1
> 3
0
motility index
< 75
>= 75
sperm density in millions per mL
<= 45
> 45
age of man in years
<= 35
> 35
fertility score =
= SUM(values for 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 4
Score
Conception Rate in 3-5 Years
14%
4%
2
26%
3
44%
4
64%
(after Figure 4, page 7)
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Purpose: To use a prognostic score based on 4 variables to estimate the rate of conception in 3-5 years for a subfertile male.
Specialty: Urology, Clinical Laboratory
Objective: severity, prognosis, stage
ICD-10: N46,
