Parameters:
(1) gender (1 if male, 2 if female)
(2) serum bilirubin in mg/dL
(3) serum alkaline phosphatase, presumably in U/L
(4) serum albumin in g/L
(5) serum potassium in mmol/L
(6) serum BUN in mg/dL
(7) prothrombin activity in percent (from 0 to 100)
where:
• The methods for determining the serum analytes are not specified.
• The reference ranges for the serum analytes are not specified.
• The units for alkaline phosphatase are not specified, but the multiplication factor from the equation below would favor U/L rather than µKat/L.
prognostic index (PI) =
= EXP(X)
X =
= (-0.8782 * (points for gender)) + (0.1449 * (serum bilirubin)) + (0.0021 * (serum alkaline phosphatase)) - (0.0746 * (serum albumin)) + (0.3437 * (serum potassium)) + (0.0299 * (BUN)) - (0.0193 * (prothrombin activity))
Interpretation:
• A low PI was <= 0.4175.
• A high PI was > 0.4175.
• A cirrhotic patient and hepatic encephalopathy has a poor prognosis and should be evaluated for liver transplant.
|
Prognostic Index (PI)
|
Survival at 1 Year
|
Survival at 3 Years
|
|
low
|
73%
|
38%
|
|
high
|
10%
|
3%
|
