The International T-Cell Lymphoma Project separated peripheral T and NK/T cell lymphomas into prognostic groups.
Parameters:
(1) pathologic type
(2) International Prognostic Index (IPI)
|
Pathologic Type |
IPI |
Prognosis (5 Year Overall Survival) |
|
primary cutaneous anaplastic LCL |
NA |
very good (100%) |
|
anaplastic LCL, ALK+ |
0 to 1 |
good (90%) |
|
anaplastic LCL, ALK+ |
4 or 5 |
guarded (33%) |
|
anaplastic LCL, ALK- |
0 to 1 |
fair to good (74%) |
|
anaplastic LCL, ALK- |
4 or 5 |
poor (13%) |
|
PTCL-NOS angioimmunoblastic |
0 to 1 |
fair (50-56%) |
|
PTCL-NOS angioimmunoblastic |
4 or 5 |
guarded to poor |
|
nasal NK/T cell subcutaneous panniculitis |
0 to 1 |
fair (57-60%) |
|
nasal NK/T cell subcutaneous panniculitis |
4 or 5 |
very poor |
|
extranasal NK/T cell adult T cell enteropathy type |
0 or 1 |
guarded (15-30%) |
|
extranasal NK/T cell adult T cell enteropathy type |
4 or 5 |
poor to very poor |
|
hepatosplenic |
NA |
very poor |
where:
• LCL = large cell lymphoma
Specialty: Hematology Oncology
