Prognostic Factors of Mournier et al from the Groupe d'Etuda des Lymphomes de l'Adulte (GELA) for Patients with Aggressive Non-Hodgkin's Lymphoma Treated by Autologous Stem Cell Transplantation (ASCT)

 

Prognostic factors:

(1) number of extranodal sites

(2) bone marrow involvement

(3) histologic type of lymphoma

(4) type of anthracycline used for chemotherapy

Parameter	Finding	Points
number of extranodal sites	0 or 1	0
	>= 2	1
bone marrow involvement	absent	0
	present	1
histologic type	nonanaplastic T cell	1
	other	0
type of anthracycline used	mitoxantrone	0
	doxorubicin	1

 

number of risk factors for decreased disease free survival (increased risk for relapse) =

= SUM(points for all 4 parameters)

 

number of risk factors for decreased overall survival =

= (points for extranodal sites) + (points for bone marrow involvement) + (points for histologic type)

 

Interpretation:

• minimum number of risk factors: 0

• maximum number of risk factors for disease free survival: 4

• maximum number of risk factors for overall survival: 3