Patient selection: first-time STEMI with reperfusion
Outcomes: cardiac death or heart failure
Echocardiographic parameters measured at 2 weeks after the STEMI (based on units in Table 2):
(1) peak E-wave transmitral flow velocity in cm/s (E)
(2) early diastolic velocity at the mitral valve annulus in m/s (e’)
(3) peak A-wave transmitral flow velocity (late diastolic wave velocity of mitral inflow) in cm/s (A)
E to e’ ratio =
= (E velocity) / (e’ velocity)
transmitral (TM) E/A ratio =
= (E velocity) / (A velocity)
where:
• The units for E and e' differ. Units described in Table 2 page 1293..
Risk factors for poor prognosis:
(1) E/e’ ratio > 15
(2) TM-E/A ratio > 1.0
An additional risk factor found on multivariate analysis was a BNP > 180 pg/mL (method TOSOH Corporation).
