Davis et al evaluated outcomes for extremely premature infants with severe intracranial hemorrhage. The authors are members of the Euince Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.
Patient selection: preterm infant born at < 27 weeks gestation with severe intracerebral hemorrhage (ICH)
Outcome: death or neurodevelopmental impairment (NDI)
Parameters:
(1) birthweight in grams
(2) presence of hemorrhagic parenchymal infarction
(3) gender
(4) unilateral vs bilateral intracerebral hemorrhage
(5) shunt
(6) postnatal steroids
(7) size of ventricle (hydrocephalus)
For all infants
|
Weight |
Infarct |
Gender |
Laterality |
Poor Outcome |
|
<= 707 grams |
no |
male |
NA |
82% |
|
<= 707 grams |
no |
female |
NA |
49% |
|
> 707 grams |
yes |
NA |
NA |
88% |
|
> 707 grams |
NA |
NA |
unilateral |
38% |
|
> 707 grams |
no |
NA |
bilateral |
48% |
|
> 707 grams |
yes |
NA |
bilateral |
76% |
For infants who are alive at 36 weeks
|
Shunt |
Postnatal Steroids |
Ventricle Size |
Poor Outcome |
|
yes |
NA |
NA |
70% |
|
no |
yes |
NA |
45% |
|
no |
no |
increased |
31% |
|
no |
no |
no |
12% |
Specialty: Neurology, Pedatrics
